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Saints vs Cardinals Odds, Lines, Spreads & Totals 2025

Cardinals
25.0 Pts
Saints
18.5 Pts
Sunday September 7, 2025 at 1:00 PM ET
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Cardinals Injury Report
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Saints Injury Report
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Cardinals Lineup
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Cardinals News
#2 RG
Will Hernandez: Out for Sunday
Sep 5th
Hernandez (knee) has been ruled out ahead of Sunday's matchup against the Saints, Bo Brack of GoPHNX.com reports.
#2 RDE
Dante Stills: Questionable after limited practice
Sep 5th
Stills (heel) is listed as questionable for Sunday's game against the Saints, Bo Brack of PHNX Sports reports.
#1 DT2
Dalvin Tomlinson: Back to health
Sep 3rd
Tomlinson (knee) isn't listed on Wednesday's injury report.
#4 LDT
Justin Jones: Placed on IR with knee injury
Aug 28th
The Cardinals placed Jones on injured reserve Thursday due to a knee injury, Darren Urban of the team's official site reports.
#3 RT
Christian Jones: Will miss at least four games
Aug 27th
Jones (knee) was placed on injured reserve Tuesday.
#2 LG
Hayden Conner: Lands on IR
Aug 27th
Conner (knee) was placed on injured reserve Tuesday.
#3 MLB
J.J. Russell: Placed on IR
Aug 26th
Russell was placed on injured reserve by the Cardinals on Tuesday, Darren Urban of the team's official website reports.
#3 RDE
Bilal Nichols: Out until October
Aug 26th
Nichols (neck) was moved to the reserve/PUP list by the the Cardinals on Tuesday, Darren Urban of the team's official website reports.
#3 SLB
BJ Ojulari: Sidelined until October
Aug 26th
Ojulari (knee) was moved to the reserve/PUP list by the Cardinals on Tuesday, Darren Urban of the team's official website reports.
#3 LDT
Walter Nolen: Set to miss early action
Aug 26th
Nolen (calf) was moved to the reserve/PUP list by the Cardinals on Tuesday, Darren Urban of the team's official website reports.
#4 RB
Bam Knight: Logs long TD run
Aug 24th
Knight racked up 83 yards and a touchdown on five carries and had one kick return for 27 yards during Saturday's 20-10 preseason win against the Raiders.
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Saints News
#3 TE
Jack Stoll: Elevated from practice squad
Sep 6th
The Saints elevated Stoll from the practice squad Saturday, Nick Underhill of NewOrleans.Football reports.
#1 LG
Trevor Penning: Sidelined for Week 1
Sep 5th
Penning (toe) has been ruled out ahead of Sunday's matchup against the Cardinals.
#1 RCB
Alontae Taylor: Cleared for Week 1
Sep 5th
Taylor (groin) doesn't have an injury designation for Sunday's game against the Cardinals, Katherine Terrell of ESPN.com reports.
#2 SS
Jordan Howden: Questionable for season opener
Sep 5th
Howden (oblique) is questionable for Sunday's game against the Cardinals, Ross Jackson of LousianaSports.net reports.
#1 SLB
Chase Young: Ruled out for Week 1
Sep 5th
Young (calf) has been ruled out for Sunday's game against the Cardinals, Mike Garafolo of NFL Network reports.
#2 NT
Khristian Boyd: Past hand injury
Sep 4th
Boyd (hand) was a full participant in Thursday's practice.
#1 LS
Zach Wood: All set for Week 1
Sep 3rd
Wood (hamstring) did not appear on the Saints' injury report Wednesday.
#1 RT
Taliese Fuaga: Healthy for Week 1
Sep 3rd
Fuaga (knee) did not appear on the Saints' injury report Wednesday.
#1 RB
Alvin Kamara: Set for workhorse role again
Sep 3rd
Saints coach Kellen Moore said Wednesday that Kamara will take most of the team's carries, with other running backs ready to step up when there's a chance, Erin Summers of NFL Network reports.
#3 LT
Barry Wesley: Will start season on IR
Aug 27th
New Orleans placed Wesley (undisclosed) on its injured reserve list with a designation to return Tuesday, Ross Jackson of WWL Louisiana reports.
#4 LT
Landon Young: Gets placed on IR
Aug 27th
New Orleans placed Young (ankle) on its injured reserve list Tuesday, Ross Jackson of WWL Louisiana reports.
#5 WR
Trey Palmer: Claimed by Saints
Aug 27th
The Saints won a waiver claim for Palmer on Wednesday, Tom Pelissero of NFL Network reports.
#5 TE
Foster Moreau: Moved to reserve/PUP list
Aug 26th
The Saints placed Moreau (knee) on the reserve/PUP list Tuesday, Ross Jackson of WWL Louisiana reports.
#4 TE
Taysom Hill: Placed on reserve/PUP list
Aug 26th
The Saints placed Hill (ACL) on the reserve/PUP list Tuesday, Nick Underhill of NewOrleans.Football reports.
#2 QB
Tyler Shough: Loses QB competition
Aug 26th
Shough will begin the regular season as the backup to Spencer Rattler, Mike Triplett of NewOrleans.Football reports.
#4 RDE
John Ridgeway: Sent to injured reserve
Aug 26th
The Saints placed Ridgeway (pectoral) on injured reserve Tuesday, Katherine Terrell of ESPN.com reports.
#1 QB
Spencer Rattler: Wins QB competition in NOLA
Aug 26th
Coach Kellen Moore has named Rattler the Saints' starting quarterback for Week 1, Mike Triplett of NewOrleans.Football reports.
#1 RILB
Pete Werner: Ready for regular season
Aug 24th
Werner logged three tackles in Saturday's 28-19 preseason loss to the Broncos.
#6 WR
Mason Tipton: Grabs one pass in preseason finale
Aug 24th
Tipton hauled in one of two targets for four yards during Saturday's 28-19 preseason loss to the Broncos.
#3 WR
Brandin Cooks: Finishes preseason with one catch
Aug 24th
Cooks recorded zero catches (on one target) during Saturday's 28-19 preseason loss to the Broncos.