Liverpool are the biggest favorites in Gameweek 4, but Arsenal aren't far behind and Viktor Gyokeres could add to his goal total, helping Fantrax and Sleeper managers.
Is this the last straw for some Liverpool players? Florian Wirtz and the Reds lead the FPL rankings with the best matchup of Gameweek 4 in a trip to Burnley.
Antoine Semenyo shined with a brace in Gameweek 1 for Fantrax and Sleeper managers and is favored to produce in Gameweek 2 for a home match against Wolves.
Arsenal disappointed in Gameweek 1 in fantasy terms, but that should change in Gameweek 2 at home against Leeds United where Bukayo Saka leads the FPL rankings.
Jeremy Doku is a great fantasy asset when he starts, something that will be a question ahead of Gameweek 1, as he expects to rank well in Fantrax and Sleeper leagues.
West Ham and Jarrod Bowen open the 25/26 season against Sunderland, and find themselves high up the Gameweek 1 FPL rankings, even in some captain discussions.
Bruno Fernandes is a talking point ahead of Fantrax and Sleeper drafts after Man United's summer additions, but he still makes the top 10 of the 2025/26 rankings.
Mohamed Salah is fresh off a monster season and unsurprisingly leads the Fantasy Premier League rankings ahead of the 2025/26 season.
Kylian Mbappe didn't stand out in the first leg, but Juan Pablo Aravena thinks that could change at the Metropolitano for one of his best bets Wednesday.
Robert Lewandowski remains one of the most lethal strikers in Europe and Luke Atzert thinks he could run rampant against a depleted Borussia Dortmund backline.
Luis Diaz and Liverpool are in flying form heading into a legendary Champions League clash against a defensively-lacking AC Milan.